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Duration of action. Although sildenafil, vardenafil, and tadalafil all work by inhibiting PDE5, tadalafil' s pharmacologic distinction is its longer half- life ( 17. delayed penis growth. best online levitra. mail order cialis online. 5 hours), compared to sildenafil and vardenafil, which are both 4– 5 hours. This translates to a longer duration of action, which is partly responsible for " The Weekend Pill" nickname. Pharmacokinetic studies evaluate the fate of a molecule introduced into the body and provide useful information that helps predict onset of action and duration of effect of that molecule.
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Duration of action of sildenafil

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